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, 1994). CoVs genomic RNA replication is mediated by RNA-directed RNA polymerase (Pol/RdRp) that is also answerable for transcription of your viral RNA genome. There is experimental evidence for SARS-CoV that nsp7 and nsp8 activate and confer processivity towards the RNA-synthesizing action on the polymerase (partitions et al., 2000). The synthesis